Mdma serotonin recovery

Added: Jaremy Ogren - Date: 07.06.2022 23:31 - Views: 28738 - Clicks: 7582

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Here we examined the long-term recovery and aging of serotonergic fibers and levels of brain-derived neurotrophic factor BDNF after intermittent MDMA administration 15 mg kg -1 i. After MDMA treatment, tryptophan hydroxylase-immunoreactive fiber density decreased and then recovered in all brain regions. There was no difference in the density of microglial cells or astrocytes in treated groups versus the control 22 months after the treatments.

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These indicate that recovery of serotonergic fibers is faster after intermittent MDMA treatment than after single-dose administration, and differences in BDNF levels per se are unlikely to for this difference. Moreover, it seems that intermittent MDMA treatment attenuates the morphological s of aging in serotonergic fibers. In addition, neither intermittent nor single-dose MDMA exposition of young animals induces accelerated aging processes or neurodegeneration in senescence, as indicated by the unaltered densities of microglial cells and astrocytes in the treated groups compared with the control.

Abstract 3,4-Methylenedioxymethamphetamine MDMA; ecstasy is a popular party drug known to cause selective serotonergic damage.

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Publication types Research Support, Non-U.

Mdma serotonin recovery

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Why take 5-HTP after MDMA? Because serotonin and science are good for you